The Best Dose Is the Lowest Dose That Works episode artwork

EPISODE · May 19, 2026 · 10 MIN

The Best Dose Is the Lowest Dose That Works

from Better Off with Victoria Reynolds

This week: why the standard GLP-1 titration protocol has a specific blind spot — and why the best dose is the lowest dose that works, not the highest dose the schedule points toward.Topics: standard titration protocol and its assumptions, the paradox of higher doses, Wegovy HD neurological signal, the flutter technique for plateaus, semaglutide first tirzepatide as escalation, what to ask your provider.LINKS & RESOURCES💉 GLP-1 protocol guide: → rx.betteroff.com/start-here and rx.betteroff.com/glp1-checklist 📘 Get the books: → rx.betteroff.com/booksBetter Off: The GLP-1 Protocol — [Amazon link coming soon] 🥤 Protein for GLP-1 patients:→ rx.betteroff.com/protein Resources → rx.betteroff.com/resources📱 Instagram: @betteroffwellnessrx.betteroff.com/books Better Off: The GLP-1 Protocol — [Amazon link coming soon]This podcast is for educational purposes. Nothing here is medical advice. Talk to your own provider before making any changes.

Episode metadata supplied by the publisher feed · Published May 19, 2026

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