The Biggest Little Troublemaker: Unpacking Lipoprotein(a) with Dr. Guy Mintz episode artwork

EPISODE · Aug 21, 2025 · 58 MIN

The Biggest Little Troublemaker: Unpacking Lipoprotein(a) with Dr. Guy Mintz

from Own Your Heart Health with Dr. Regina Druz · host Dr. Regina Druz

Lipoprotein(a) might be one of the most important pieces of the heart health puzzle that most people have never heard about.   Dr. Regina Druz sits down with cardiologist and lipidology expert Dr. Guy Mintz to discuss why this particle deserves far more attention in cardiology. Lipoprotein(a) is often left out of standard cholesterol tests, yet it is linked to early heart attacks, strokes, valve disease, and aggressive atherosclerosis. If lowering cholesterol only cuts cardiovascular risk in half, what explains the rest? Could Lipoprotein(a) be the missing factor that shapes a person’s long-term health?   The conversation looks closely at the science behind Lipoprotein(a), its genetic roots, and why doctors call it a “genetic tattoo.” You’ll hear why every adult should ask for this test, why family members of those with elevated levels need screening, and how new drugs in development may soon lower Lipoprotein (a) by up to 90%. Until then, heart attack prevention depends on various steps like lifestyle choices, aggressive cholesterol control, and in some cases, apheresis.   This episode encourages a broader view of heart health, one that goes beyond LDL cholesterol to include genetics, inflammation, and personalized care. What would change if you knew your Lipoprotein(a) level? How would that knowledge shape the way you approach prevention?   Episode Breakdown: 00:00 Lipoprotein(a) and the Future of Heart Health 04:49 Why Lipoprotein(a) Raises Heart Attack and Stroke Risk 14:13 Genetics of Lipoprotein(a) and Family Screening 27:18 Should Lipoprotein(a) Be in Standard Cholesterol Tests 35:12 New Therapies to Lower Lipoprotein(a) 52:29 Residual Risk and Heart Attack Prevention   Links Schedule a Discovery Call Access Courses and Events Get Heartwell Toolkits Schedule a Business Meeting   Connect with Dr. Regina Druz: Holistic Heart Centers Website YouTube Instagram Facebook X TikTok Podcast production and show notes provided by HiveCast.fm

Lipoprotein(a) might be one of the most important pieces of the heart health puzzle that most people have never heard about.   Dr. Regina Druz sits down with cardiologist and lipidology expert Dr. Guy Mintz to discuss why this particle deserves far more attention in cardiology. Lipoprotein(a) is often left out of standard cholesterol tests, yet it is linked to early heart attacks, strokes, valve disease, and aggressive atherosclerosis. If lowering cholesterol only cuts cardiovascular risk in half, what explains the rest? Could Lipoprotein(a) be the missing factor that shapes a person’s long-term health?   The conversation looks closely at the science behind Lipoprotein(a), its genetic roots, and why doctors call it a “genetic tattoo.” You’ll hear why every adult should ask for this test, why family members of those with elevated levels need screening, and how new drugs in development may soon lower Lipoprotein (a) by up to 90%. Until then, heart attack prevention depends on various steps like lifestyle choices, aggressive cholesterol control, and in some cases, apheresis.   This episode encourages a broader view of heart health, one that goes beyond LDL cholesterol to include genetics, inflammation, and personalized care. What would change if you knew your Lipoprotein(a) level? How would that knowledge shape the way you approach prevention?   Episode Breakdown: 00:00 Lipoprotein(a) and the Future of Heart Health 04:49 Why Lipoprotein(a) Raises Heart Attack and Stroke Risk 14:13 Genetics of Lipoprotein(a) and Family Screening 27:18 Should Lipoprotein(a) Be in Standard Cholesterol Tests 35:12 New Therapies to Lower Lipoprotein(a) 52:29 Residual Risk and Heart Attack Prevention   Links Schedule a Discovery Call Access Courses and Events Get Heartwell Toolkits Schedule a Business Meeting   Connect with Dr. Regina Druz: Holistic Heart Centers Website YouTube Instagram Facebook X TikTok Podcast production and show notes provided by HiveCast.fm

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The Biggest Little Troublemaker: Unpacking Lipoprotein(a) with Dr. Guy Mintz

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Frequently Asked Questions

How long is this episode of Own Your Heart Health with Dr. Regina Druz?

This episode is 58 minutes long.

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This episode was published on August 21, 2025.

What is this episode about?

Lipoprotein(a) might be one of the most important pieces of the heart health puzzle that most people have never heard about.   Dr. Regina Druz sits down with cardiologist and lipidology expert Dr. Guy Mintz to discuss why this particle deserves far...

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