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EPISODE · Jul 22, 2025 · 32 MIN

The Bliss Gene And The Burden Of Mood

from The Gist · host Mike Pesca

Psychiatrist Richard A. Friedman explains how a rare genetic mutation affecting the enzyme FAAH, and a ubiquitous neurotransmitter called Anandamide may account for unusually low anxiety, reduced drug cravings, and an innate buoyancy, the type of which you might find in a daily podcast host. Plus, Louisville reverses its immigration detainer policy under federal pressure, reigniting the debate over sanctuary cities and local autonomy. And in the Spiel a burial standoff concerning the former President of Zambia. Produced by Corey Wara Production Coordinator Ashley Khan Email us at ⁠⁠⁠⁠[email protected]⁠⁠⁠⁠ To advertise on the show, contact ⁠⁠⁠⁠[email protected]⁠⁠⁠⁠ or visit ⁠⁠⁠⁠https://advertising.libsyn.com/TheGist⁠⁠⁠⁠ Subscribe to The Gist: ⁠⁠⁠⁠https://subscribe.mikepesca.com/⁠⁠⁠⁠ Subscribe to The Gist Youtube Page: ⁠⁠⁠⁠https://www.youtube.com/channel/UC4_bh0wHgk2YfpKf4rg40_g⁠⁠⁠⁠ Subscribe to The Gist Instagram Page: ⁠⁠⁠⁠GIST INSTAGRAM⁠⁠⁠⁠ Follow The Gist List at: ⁠⁠⁠⁠Pesca⁠⁠⁠⁠ ⁠⁠⁠⁠Profundities | Mike Pesca | Substack⁠⁠⁠⁠ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Episode metadata supplied by the publisher feed · Published Jul 22, 2025

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