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EPISODE · May 18, 2026 · 36 MIN

The Brain-Hormone Conversation

from Functional Wellness with Dr. Alison · host Dr. Alison DiBarto Goggin

The Brain-Hormone Conversation Estrogen, Progesterone, Thyroid, the Estrobolome, and the Woman in the Middle of It All If your labs are normal but your brain is anything but, this episode is for you. Dr. Alison goes deep on the hormone-brain connection in Episode 3 of the May brain health series. Estrogen as a brain hormone. Progesterone as the brain’s calming hormone through allopregnanolone and the GABA system. Thyroid as the metabolic gas pedal, and why standard TSH testing misses most of the picture. And the estrobolome, the gut microbiome system that actively recycles and regulates your estrogen from inside your intestines. Includes the labs to actually ask for, why bioidentical progesterone is not the same as synthetic progestins, and why perimenopausal brain symptoms often start years before cycles change. Topics covered: estradiol and neurotransmitters, perimenopausal brain imaging, glucose regulation in the brain, progesterone and allopregnanolone, GABA, bioidentical hormone replacement, full thyroid panels, Hashimoto’s thyroiditis, the estrobolome, beta-glucuronidase, gut-hormone axis, DUTCH testing. The Mama Brain Reset Doors close Sunday May 24 at midnight. The 30-day root cause program for the perimenopausal brain, the post-viral brain, and the woman whose mind has gone quiet. Investment $247 all-in. Comment MAMA on Dr. Alison’s Facebook posts or visit https://alisondibartogoggin.podia.com/mama-brain Feminine Medicine Class Wednesday May 20: Brain Medicine and the Sacred Mind. Link in description. Discount for The Mama Brain Reset for attendees. https://www.facebook.com/events/1631961514728671 Subscribe to the series Episode 4: The Forgotten Brain Foundations (drops May 25, the day the cohort begins).

Episode metadata supplied by the publisher feed · Published May 18, 2026

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The Brain-Hormone Conversation

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