The Brain's Hidden Immune System: Why Everything You Know About Alzheimer's & Your Nervous System Is Wrong | Dr. David Perlmutter

Dr. David Perlmutter — neurologist, New York Times bestselling author, and author of the new book Brain Defenders — joins Dr. Will Cole to reveal what he believes is the most important breakthrough in brain health science in decades: the microglial cell. He explains why the amyloid hypothesis that has dominated Alzheimer's research (and pharmaceutical spending) for 30 years has been definitively disproven by a Cochrane analysis, why a Harvard lifestyle study arrested Alzheimer's decline in 70% of patients without any drug, and what the April 2024 NEJM GLP-1 Parkinson's trial means for the future of neurodegenerative disease. They also cover the practical daily habits, foods, supplements, and lab tests that shift the brain's immune cells from destructive to protective — and why you are far more the architect of your brain's destiny than anyone has told you. For all links mentioned in this episode, visit http://www.drwillcole.com/podcastPlease note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Take the first step and learn at a pace that works for you. Visit WaldenU.edu.Give them meals + snacks that are actually right for where kids are developmentally - balanced, intentional and made to support real growth. Go to littlespoon.com/WILLCOLE and enter code WILLCOLE for 30% off your first order.Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at drinklmnt.com/artofbeingwell. Find your favorite flavor, or share with a friendQUINCE.COM/WILLCOLE for free shipping and 365 day returns. Now available in Canada too! www.jshealthvitamins.com code WILLCOLE for 15% off at checkout LIFT Oléoactif® significantly reduced the primary wrinkle by more than 200%.† OR 200% reduction in wrinkles with LIFT Oléoactif®†* Disclaimer: *Clinical test: LIFT Oléoactif® in cream, results in 28 days, compared to placebo. LIFT Oléoactif® is a trademark of HALLSTAR FRANCE SAS. 95% see a reduction in eyebag volume* with Eyeseryl® Peptide Disclaimer: *Clinical test: EYESERYL® Peptide in cream, results in 28 days. EYESERYL® Peptide is a trademark of Lubrizol Advanced Materials, Inc. or its affiliates.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.