The Effects of Long-Term Hormone Therapy for Midlife Women episode artwork

EPISODE · Jan 1, 2026 · 17 MIN

The Effects of Long-Term Hormone Therapy for Midlife Women

from Women's Healthspan Voices with Dr. Pat McShane · host Pat McShane, MD

Learn when and how to stop hormone therapy, the real risks and benefits, and what research shows about menopause, aging, and long-term health.In this episode, I’m joined by Dr. Nanette Santoro to discuss how long women can safely use hormone therapy and how to approach tapering off. We explore how age, duration, and hormone type affect risk, what the Women’s Health Initiative and SWAN studies have taught us, and why the menopause transition is a critical time for cardiovascular and metabolic health. We also talk about treating symptoms and staying proactive with preventive care.Dr. Nanette Santoro is an internationally recognized menopause researcher, clinician, and Professor of Obstetrics and Gynecology at the University of Colorado, where she holds the E. Stewart Taylor Chair. She is a member of the Division of Reproductive Endocrinology and Infertility. She has served as a principal investigator in major NIH-funded studies, including the SWAN study, which has followed women through the menopause transition for more than two decades.Dr. Pat McShane, MDLinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/pat-mcshane-0535ba3/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.womenshealthspan.netYouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@mcshanepmcshane9303⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Produced by DrTalks: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/podcast/

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