The Gut-Brain-Dementia Connection

A new study by a GW-led research team suggests gut bacteria may be linked to memory decline in mild cognitive impairment, or MCI, and some dementia diseases. Published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association, the scoping review is shedding light on the growing evidence that gut microbiome imbalances—known as dysbiosis—may play a key role in the development and progression of MCI and Alzheimer’s disease. Today, we have with us two of the study’s lead authors—Drs. Leigh Frame and Alison Warren of the GW School of Medicine and Health Sciences and the Frame-Corr Lab. Dr. Frame is an expert on the gut microbiome, co-leader of the lab, executive director of the Office of Integrative Medicine & Health, and an associate professor here at GW. Dr. Warren is a doctoral student in the Translational Health Sciences PhD Program here at GW and an adjunct assistant professor. She is collaborating with the Frame-Corr Lab in microbiome studies associated with mild cognitive impairment and Alzheimer’s disease. Drs. Frame and Warren are all on the faculty of the Institute for Brain Health & Dementia at the GW Milken Institute School of Public Health. Dr. Misha Kogan, an integrative geriatrician, expert on dementia diseases, and also institute faculty, is the co-host on this episode. ◘ Related Links: GW Press Release: https://bit.ly/3NXSZ4l; Journal Article: The microbiota–gut–brain axis in mild cognitive impairment and Alzheimer's disease: a scoping review of human studies, https://bit.ly/3ZsPmWV; Frame-Corr Lab: https://framecorrlab.smhs.gwu.edu/ ◘ Transcript: bit.ly/3JoA2mz ◘ This podcast features the song “Follow Your Dreams” (freemusicarchive.org/music/Scott_Ho…ur_Dreams_1918) by Scott Holmes, available under a Creative Commons Attribution-Noncommercial (01https://creativecommons.org/licenses/by-nc/4.0/) license. ◘ Disclaimer: The content and information shared in GW Integrative Medicine is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in GW Integrative Medicine represent the opinions of the host(s) and their guest(s). For medical advice, diagnosis, and/or treatment, please consult a medical professional.