The Hormone Reset: Understanding the Endocrine and Immune Shifts of Perimenopause and Their Fertility Implications

As fertility declines with age, it's not just about egg quantity—it's about the entire hormonal and immune environment surrounding the ovaries. In this episode of The Egg Factor, CHR’s physicians break down the nuanced changes that happen in the late 30s and 40s, including shifts in estrogen, testosterone, and DHEA levels—and how these changes impact ovarian function and embryo quality.Listen now on Spotify, Apple Podcasts, or wherever you get your podcasts.Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the forefront of fertility care since the beginning. Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.Website: www.thechr.com Facebook: https://www.facebook.com/chrnewyork Instagram: https://www.instagram.com/chrnewyork/ Linkedin:  https://www.linkedin.com/company/centerforhumanreproduction/ Pinterest: https://www.pinterest.com/CenterforHumanReproduction/ TikTok: https://www.tiktok.com/@chrnewyork