The Laughing Sickness: Medicine’s Strangest Cold Case episode artwork

EPISODE · Aug 3, 2026 · 23 MIN

The Laughing Sickness: Medicine’s Strangest Cold Case

from Mysteries and Histories · host Georgia Marie

In the isolated highlands of Papua New Guinea, a strange and horrifying disease spread through entire villages, leaving women and children trembling, stumbling, and erupting into sudden fits of laughter before wasting away to death. For years, no one knew what was killing them, and the answer turned out to be far more disturbing than anyone expected: a fatal prion disease tied to one of the greatest human taboos.

Episode metadata supplied by the publisher feed · Published Aug 3, 2026

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The Laughing Sickness: Medicine’s Strangest Cold Case

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