The Lead Podcast - Episode 110: A Discussion of Left bundle area pacing in hypertrophied hearts...LIVE from HRS 2025 in San Diego

Left Bundle Area Pacing in Hypertrophied Hearts: An Ex Vivo Ovine Model to Study Deployment of Pacing Leads in Thick Septum describes the development of a novel ex vivo sheep heart model with induced septal hypertrophy to simulate challenging left bundle branch area pacing (LBBAP) scenarios. The study evaluates the deployment characteristics and fixation behavior of pacing leads in thickened septal tissue, aiming to improve procedural safety and lead placement strategies in patients with left ventricular hypertrophy. This model offers a valuable tool for preclinical testing and refinement of lead technologies and techniques. https://www.hrsonline.org/education/TheLead https://pubmed.ncbi.nlm.nih.gov/40294732/ Host Disclosure(s): D. Raja: Nothing to disclose. Contributor Disclosure(s): P. Sharma: Honoraria/Speaking/Consulting: Medtronic, Abbott, Biotronik