The liver ingredient that might be more valuable for diabetes

Silymarin has been "the liver ingredient" for 2,000 years. But silybin (the most active flavonolignan in silymarin) activates IRS-1 phosphorylation and GLUT4 translocation core mechanisms of insulin sensitivity and glucose uptake. With 25% of the global population having NAFLD/MAFLD, the metabolic health repositioning of silymarin could be worth more than its entire current liver health market.Publications of interest:https://pubmed.ncbi.nlm.nih.gov/25760026/https://pubmed.ncbi.nlm.nih.gov/24036369/https://pubmed.ncbi.nlm.nih.gov/32950646/