The Minor Intron Lights

This release contains only the music track from Base by Base Episode 318. Song title: The Minor Intron LightsOriginal Base by Base episode: 318: RNU6ATAC variants cause U6atac-driven minor spliceopathy with transcriptome-wide minor intron retentionOriginal episode link: https://basebybase.com/episodes/rnu6atac-minor-spliceopathy Article metadata:Article title: Biallelic Variants in RNU6ATAC Result in a Minor Spliceopathy Characterized by Transcriptome-Wide Minor Intron Retention Events and Short Stature with Variable Multisystem ManifestationsJournal: Human Genetics and Genomics Advances, Journal Pre-proofDOI: 10.1016/j.xhgg.2026.100588Reference: Mendez R, Arriaga TM, Ma J, Bonner DE, Emami S, Levy RJ, Alsagheir A, Alhaddad B, Bakur K, Ungar RA, Matalon DR, Miller AM, Nguyen J, Smith KS, Scott SA, Liao L, Ng Z, Marwaha S, Ward A, Undiagnosed Diseases Network, Genomics Research to Elucidate the Genetics of Rare Diseases Consortium, Novacic D, Alkuraya FS, Bernstein JA, Ganesh VS, O’Donnell-Luria A, Montgomery SB, Wheeler MT, Biallelic Variants in RNU6ATAC Result in a Minor Spliceopathy Characterized by Transcriptome-Wide Minor Intron Retention Events and Short Stature with Variable Multisystem Manifestations, Human Genetics and Genomics Advances (2026), doi: https://doi.org/10.1016/j.xhgg.2026.100588 Lyrics:Verse 1In the quiet lanes of a folded strand,A hidden rhythm slips from hand to hand.Little doors in the message don’t close on time,And the whole wide chorus falls out of line. Pre-ChorusWe traced the tremor through the script tonight,From the smallest splice to the body’s fight.Two tiny changes, and the gears misfire—Hear that heartbeat under wire. ChorusTurn on the minor intron lights,Let the small cuts make sense of nights.When the words get stuck, we read them through,Find the break, find the thread, find you. Verse 2A short horizon, bones and breath,Signals tangled in the shade of health.Blood and skin cells, the same refrain:A subtle fault with a wide-spread pain. BridgeNot every clue is loud and clear,Some are whispers you can only hearWhen you line up the reads, let patterns speak,And follow the missing where it leaks. Final ChorusTurn on the minor intron lights,Let the small cuts make sense of nights.If the splice runs slow, we won’t let go—Name the glitch, map the cause, help life grow.