The Missing Treatment Layer: Daily Support That Improves Treatment Tolerance and Completion

In this new OncoPod episode, Dr. Christopher R. Cogle (University of Florida) and Dr. Neil M. Iyengar (Winship Cancer Institute at Emory University) discuss an often-overlooked gap in oncology care - the absence of a structured, non-pharmaceutical treatment layer to help patients stay on therapy and recover stronger.Drawing on findings from the CHALLENGE trial (NEJM, 2025) and their clinical experience, the experts outline how daily lifestyle interventions in exercise, nutrition, and stress management can improve treatment tolerance, adherence, and even survival. They also explore why these evidence-based approaches have yet to become standard practice and how platforms like Complement 1 are operationalizing integrative oncology at scale, making these interventions accessible to patients beyond major academic centers.