The New Hit Depression Treatment? A Ketamine-Derived Nasal Spray

from The Journal. · host The Wall Street Journal & Spotify Studios

After it was approved in 2019, Spravato, a depression treatment derived from the club drug ketamine, was looking like a dud. But recently it has taken off, and it surpassed $1 billion in annual sales last year for its maker, Johnson and Johnson. Further Listening: -A Lawyer Says He Doesn't Need Help for Psychosis. His Family Disagrees. -America's Maternal Mental Health Crisis Further Reading: -J&J’s Ketamine-Derived Drug Is Taking Off -Big Pharma Walked Away From Mental Health. Why Some Are Coming Back. Learn more about your ad choices. Visit megaphone.fm/adchoices

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This episode was published on March 21, 2025.

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