The Nobel Prize in Physiology or Medicine 2025 explained!

from Microbial Mondays · host Merel Sijbranda and Alex Cloherty

Have you ever wondered how our immune system finds the balance in attacking invading viruses and bacteria that try to enter our bodies, but not attacking our own body cells? The groundbreaking discoveries concerning this topic, called 'peripheral immune tolerance', by Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi were awarded the Nobel Prize in Physiology or Medicine 2025! It tells us a lot about how the immune system functions in health and disease!In this episode, we dive into:the discoveries that led to winning this year's Nobel Prize, Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi's journey to get to these discoveries,what impact these discoveries have had in the past, still have now, and will have in the future!This podcast episode was created based on the Popular Science Background and Scientific Background published on nobelprize.org . If you are interested in learning more, read here: https://www.nobelprize.org/prizes/medicine/2025/press-release/

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