The OJC Episode 34: A Manifesto for Good Trial Design

Send us Fan MailThe Oncology Journal Club - Delivering Oncology News DifferentlyThe Oncology Podcast, brought to you by Oncology News Australia, is proud to present Episode 34 in our series The Oncology Journal Club.This week we have another great episode for you in our usual format. Craig Underhill gets us started by talking us through primary tumour resection plus chemotherapy versus chemotherapy alone for metastatic colorectal cancer patients.Hans Prenen gets stuck into the use of tipifarnib in head and neck squamous cell carcinoma with HRAS mutations and Eva Segelov continues to guide us through what she calls a ‘manifesto for good study design’ – a key paper from our friend Bishal Gyawali, addressing biases in study design that distort the appraisal of clinical benefit.Just a quick note – Eva started her analysis of this paper in last week’s episode so I recommend listening to Episode 33 if you’ve not already. Today’s quick bites are as diverse as ever covering estimates for cancer incidence and death to 2040, plasma cfDNA genotyping, the CROSS trial, targeting metabolism to enhance immunotherapy and an excellent paper by our friend Heidi Probst on the patient experience of radiotherapy for breast cancer. If you’re not familiar with Heidi check out Episode 32 ‘When the Oncologist gets cancer’.With the usual top quality banter, papers you won’t hear of anywhere else and expert analysis from our Hosts, you are in for another great episode of The Oncology Journal Club!Full bios and the list of all papers discussed are available on our website.For the latest oncology news visit www.oncologynews.com.au and for regular oncology updates for healthcare professionals, subscribe for free to get the weekly The Oncology Newsletter.The Oncology Podcast - An Australian Oncology Perspective