The Pauling Principle Episode 22 - Bolz-2, Boltzgen and foundational models for molecules episode artwork

EPISODE · Nov 3, 2025 · 1H 1M

The Pauling Principle Episode 22 - Bolz-2, Boltzgen and foundational models for molecules

from The Pauling Principle · host PAULING.AI

Is protein folding solved? Not quite, even though the progress has been tremendous since the first AlphaFold and up to last year's Nobel prize. The team behind Boltz and Boltz-2, from MIT CSAIL and Jameel Clinic, just released Boltzgen, a state of the art model for protein design. In this chat with Gabriele Corso I review the progress in the field and whats next.

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The Pauling Principle Episode 22 - Bolz-2, Boltzgen and foundational models for molecules

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