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EPISODE · Jun 16, 2026 · 38 MIN

The Predictive Mind

from The Backward Step · host Anuj

What if everything you perceive is your brain’s best guess not reality itself? In this first episode, we explore a 2021 paper by Ruben Laukkonen and Heleen Slagter that bridges cutting-edge neuroscience with ancient contemplative wisdom, and finds they’ve been describing the same thing from opposite directions.We cover the Predictive Processing framework the idea that your brain is a prediction machine, sealed in darkness, running a controlled hallucination we call reality. We trace what this means for consciousness, for suffering, for the Default Mode Network, and for the self. And we follow the thread all the way through to what meditation actually does, mechanically, to the architecture of the mind and why that matters for depression, anxiety, and the therapeutic process.Paper Referenced: “From Many to N-one: Meditation and the Plasticity of the Predictive Mind”  Laukkonen & Slagter, Neuroscience and Biobehavioral Reviews, 2021.Topics: Predictive Processing · Bayesian Brain · Default Mode Network · Focused Attention · Open Monitoring · Radical Plasticity · Ego dissolution · Psychedelics & therapy · Dukkha · Dogen · Therapy · ACT Therapy · Mindfulness · Meditation

Episode metadata supplied by the publisher feed · Published Jun 16, 2026

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What if everything you perceive is your brain’s best guess not reality itself? In this first episode, we explore a 2021 paper by Ruben Laukkonen and Heleen Slagter that bridges cutting-edge neuroscience with ancient contemplative wisdom, and finds they’ve been describing the same thing from opposite directions. We cover the Predictive Processing framework the idea that your brain is a prediction machine, sealed in darkness, running a controlled hallucination we call reality. We trace what t...

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The Predictive Mind

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