The promise of translational and personalised approaches for paediatric obstructive sleep apnoea

Obstructive sleep apnoea (OSA) can result in significant morbidities including the cardiovascular, metabolic and neurocognitive systems. While great advances have been made in sleep medicine research in the past decades, there are still wide gaps in our knowledge concerning the exact underlying pathophysiological mechanisms of OSA and consequences. A recent review in Thorax discusses the recent exciting discoveries in genotype-phenotype interactions, epigenetics, genomics and proteomics related to OSA. Thorax editor Andy Bush talks to co-author David Gozal, professor in the Department of Pediatrics, The University of Chicago, about the highlights. Read the full paper: The promise of translational and personalised approaches for paediatric obstructive sleep apnoea: an ‘Omics’ perspective http://goo.gl/fKf28O