The real active in ginseng might not be a ginsenoside at all

Compound K (CK), the primary gut metabolite of PPD-type ginsenosides, is more potent than the parent compounds for anti-inflammatory, anti-cancer, and anti-diabetic activity. Only ~30% of people efficiently produce Compound K (microbiome-dependent). This means ginseng is a different drug in different people. Direct Compound K supplementation could bypass the microbiome variability entirely.Publications of interest:https://pubmed.ncbi.nlm.nih.gov/32617041/https://pubmed.ncbi.nlm.nih.gov/31984805/https://pmc.ncbi.nlm.nih.gov/articles/PMC6026358/