The Real Reason Behind Most DeFi Hacks episode artwork

EPISODE · May 13, 2026 · 35 MIN

The Real Reason Behind Most DeFi Hacks

from a16z crypto show · host Andreessen Horowitz

Following a string of major DeFi exploits, we unpack what’s driving the recent rise in hacks across crypto. a16z crypto GP Eddy Lazzarin and security engineer Matt Gleason join host Robert Hackett to take a closer look. Their argument: AI is not introducing entirely new vulnerabilities. It is making existing weaknesses easier to identify and exploit. The question is whether defenders can evolve as quickly as attackers. They also cover: - why “AI-powered hacking” is difficult to measure - how geopolitical tensions may be influencing cyber activity - why defenders should be aggressively stress-testing their own systems - how AI could eventually outperform humans at resisting social engineering - what users can do today to protect themselves online   Timestamps: 00:00 - Intro 00:57 - The surge, explained 01:37 - Did attackers use AI 04:19 - How AI can help defend against attacks 09:16 - The doomsday marketing debate 17:17 - DeFi transparency: opportunities and challenges 21:00 - Social engineering and how to stay safe   Follow along here: Eddy Lazzarin: https://twitter.com/eddylazzarin Robert Hackett: https://twitter.com/rhackett Matt Gleason: https://twitter.com/mg_486662 Follow a16z crypto: X: https://twitter.com/a16zcrypto LinkedIn: https://www.linkedin.com/showcase/a16zcrypto/posts/ YouTube: https://www.youtube.com/@a16zcrypto Subscribe for more industry reports, trend updates, news analysis, builder guides, and other resources: https://a16zcrypto.substack.com/subscribe/   As always, none of the following should be taken as investment, business, legal, or tax advice. Please see a16z.com/disclosures for more important information, including a link to a list of our investments. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Episode metadata supplied by the publisher feed · Published May 13, 2026

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Following major DeFi exploits, a16z crypto GP Eddy Lazzarin and security engineer Matt Gleason break down the recent surge in crypto hacks. Their argument: AI isn't creating new vulnerabilities—it's making existing ones easier to exploit. They explore whether defenders can evolve as fast as attackers, the role of geopolitics in cyber activity, and what users can do to stay safe online.

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The Real Reason Behind Most DeFi Hacks

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