The Real Risk: Understanding Plaque Burden and Individualized LDL Targets for Heart Health episode artwork

EPISODE · May 28, 2026 · 20 MIN

The Real Risk: Understanding Plaque Burden and Individualized LDL Targets for Heart Health

from CardioNow · host TopHealth Media

Welcome back to Cardio NOW, the podcast where we redefine how you think about heart health. In this episode, cardiologist Dr. Mahesh Mulumudi challenges traditional approaches to cholesterol and heart disease prevention. Instead of focusing on population averages and arbitrary LDL targets, he digs into the science of personalized risk, exploring how your unique plaque burden, inflammation levels, and genetics determine your true cardiovascular risks.From the latest research on omega-3s and plaque regression to the hidden dangers of inflammation and the role of novel markers like Lp(a) and apolipoprotein B, today’s conversation will transform the way you partner with your doctor and manage your heart health. Whether you’re aiming for lower numbers or looking to understand what those numbers really mean, this episode will equip you with the critical questions you need to ask and the actionable steps that can make a difference. So get ready to go beyond the standard checkup; your heart will thank you.Timestamps:00:00 Debating LDL number personalization04:50 Traditional cardiology practices questioned09:05 Understanding LDL and inflammation12:36 Managing inflammation and heart health13:25 Exercise after meals to reduce glucose17:40 Cholesterol testing recommendations20:04 Understanding personal health targetsDr. Mahesh Mulumudi LinkedIn - https://www.linkedin.com/in/mahesh-mulumudi-1ba8733CardioNow - https://www.cardionow.org/about-us/our-providers/mahesh-mulumudi-md-facc-fscai/CardioNow YouTube - https://www.youtube.com/@CardioNowPLLCTopHealth Media Network - https://tophealth.care/Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Welcome back to Cardio NOW, the podcast where we redefine how you think about heart health. In this episode, cardiologist Dr. Mahesh Mulumudi challenges traditional approaches to cholesterol and heart disease prevention. Instead of focusing on population averages and arbitrary LDL targets, he digs into the science of personalized risk, exploring how your unique plaque burden, inflammation levels, and genetics determine your true cardiovascular risks. From the latest research on omega-3s and p...

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The Real Risk: Understanding Plaque Burden and Individualized LDL Targets for Heart Health

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This episode was published on May 28, 2026.

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Welcome back to Cardio NOW, the podcast where we redefine how you think about heart health. In this episode, cardiologist Dr. Mahesh Mulumudi challenges traditional approaches to cholesterol and heart disease prevention. Instead of focusing on...

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