The Role of ApoB in Cardiovascular Disease

Adequate risk assessment and management are crucial in preventing cardiovascular disease. A recent study examined the correlation between common measures of cholesterol concentration versus the number of apolipoprotein B (apo-B)-containing lipoproteins. In other words, should clinicians use different biomarkers for cardiovascular risk assessment? Cardiology Pharmacist, Lindsay Davis, joins Geoff Wall in this discussion.The GameChanger Evidence is emerging to suggest apo-B is a more accurate biomarker of MI risk. While not routinely evaluated, apo-B is a GameChanger in that it can be helpful in determining cardiovascular risk in patients with borderline risk factors.   Show Segments 00:00 – Introductions 03:22 – Apolipoprotein B (apo-B) 05:22 – Biomarkers for Cardiovascular Disease 12:58 – The GameChanger 20:37 – Connecting to Practice 28:49 – Closing Remarks HostGeoff Wall, PharmD., BCPS, FCCP, CGPProfessor of Pharmacy Practice, Drake University Internal Medicine/Critical Care, UnityPoint HealthGuest: Lindsay Davis, PharmD, BCPS, BCCP, TTS, ASH-CHCProfessor, Midwestern UniversityLindsay Davis has no relevant financial relationships to discuss. References and resources:Association of Apolipoprotein B–Containing Lipoproteins and Risk of Myocardial Infarction in Individuals With and Without Atherosclerosis Distinguishing Between Particle Concentration, Type, and ContentAMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF DYSLIPIDEMIA AND PREVENTION OF CARDIOVASCULAR DISEASEPrimary biliary cirrhosis, hyperlipidemia, and atherosclerotic risk: a systematic review2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice GuidelinesRedeem your CPE or CME creditCPE (Pharmacists)CME (Physicians)Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode) Pharmacists: Get a membershipPrescribers: Get a membershipContinuing Education Information:Learning Objectives:1. Describe the role of apolipoprotein B in cardiovascular management2. Identify patients that may benefit from apolipoprotein B testingAll relevant financial relationships have been mitigated.  0.05 CEU | 0.5 HrsACPE UAN: 0107-0000-22-232-H01-PInitial release date: 06/20/22Expiration date: 06/20/2023Additional CPE & CME details can be found hereFollow CEimpact on Social Media:LinkedInInstagram