The Science Behind Effective Skincare with Scott Futterman and Samuel Raoof of DRMTLGY

Send us Fan MailIn this episode of Skin Anarchy, Dr. Ekta Yadav sits down with DRMTLGY co-founders Scott Futterman and Samuel Raoof for a conversation that cuts through one of the beauty industry’s biggest misconceptions: that great skincare is defined by ingredient lists alone. In a market flooded with trending actives, viral products, and marketing claims, they offer a rare look at what actually determines whether a product performs. The story begins long before DRMTLGY entered the consumer market. Raised around dermatology, Samuel developed a deep appreciation for skin science and eventually recognized a gap in physician-dispensed skincare. Rather than relying on existing manufacturers, he built his own facility to create formulations that met the standards dermatologists were seeking. Years later, Scott saw an opportunity to make those same products more accessible, helping transform DRMTLGY into one of the most recognized science-driven skincare brands today. Throughout the episode, the founders challenge the industry’s obsession with ingredient names and buzzwords. A product’s effectiveness, they explain, depends on far more than whether it contains vitamin C, retinol, or peptides. Stability, delivery systems, concentration, bioavailability, and formulation architecture all influence whether an ingredient can actually perform inside the skin. The conversation also pulls back the curtain on product development—from stability studies and preservative testing to finished-formula clinical trials. Rather than relying on supplier claims, DRMTLGY evaluates how ingredients behave within the final formulation, where real-world performance is determined. Listen to the full episode to hear Scott Futterman and Samuel Raoof explain why formulation matters more than buzzwords—and why efficacy should remain the standard by which skincare is judged.SHOP DRMTLGYDon’t forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform.Reach out to us through email with any questions.Sign up for our newsletter!Shop all our episodes and products mentioned through our ShopMy Shelf!*This is a paid collaborationSupport the show