The Skincarma Pod | Ep. 58: Not All Exosomes Are Created Equal – Plated CEO Alisa Lask on Platelet-Derived vs. Plant-Derived Exosomes

In this episode of The Skincarma Pod, Carmine sits down with Alisa Lask, CEO of Rion Aesthetics and the medical-grade skincare line Plated Skin Science. Together, they unpack what’s real – and what’s hype – in the fast-emerging world of exosomes in skincare.Alisa shares her path from Midwest beginnings and a career across Eli Lilly, Allergan, and Galderma, to leading a regenerative aesthetics company built on platelet-derived exosome technology – a category Plated helped bring into the skincare conversation.Carmine and Alisa dive into:What exosomes are (Alisa’s simple “text messaging system” explanation);Why platelet-derived exosomes are fundamentally different from plant-based “exosome” claims;Plated’s origin story rooted in the Mayo Clinic’s Van Cleve Cardiac Regenerative Medicine Program;How Plated sources material from FDA-compliant platelet banks (and why transparency matters);Why Plated is provider-dispensed, not built for big-box beauty retail;Plus: murder-mystery comfort TV, safari travel, dog rescue, and the lightning-round line you won’t forget: “I feel most like myself when…I’m in the barn.”Curious about exosomes? Explore Carmine’s article 2025 Ingredient Trends: Exosomes Are One Part Science, One Part Story on Substack here.Connect with Alisa on Instagram at @alisa.lask_rion and on LinkedIn here. Explore Plated Skin Science on Instagram at @platedskinscience and learn more about the products, exosome science and brand ethos at platedskinscience.com.Follow Skincarma on Instagram and on TikTok. Catch product reviews of Carmine’s top picks of the best skincare on the Skincarma Blog. You can also connect with Carmine on LinkedIn here and explore his extensive work in beauty on the Carmine Montalto INK website here.If you enjoyed this episode, please subscribe, rate and/or leave a review on Apple Podcasts, Substack, or Spotify to help Carmine reach more curious listeners.Product links: Plated Intense SerumPlated Daily SerumPlated Hair Serum—Product reviews on the Skincarma Blog:Explore the Best Sunscreens for Face here.Explore the Best Retinol Face Creams and Serums here.Explore the Best Vitamin C Serums here.Explore the Best Niacinamide Serums here.Explore the Best Acne Treatments here.Explore the Best Anti-Aging Creams and Serums here.Explore the Best Face Creams for Dry Skin here.Explore the Best Face Creams for Oily Skin here.The Skincarma® Pod is where indie beauty meets fearless curiosity. Hosted by Carmine, his podcast pulls back the curtain on the beauty industry with sharp insights, candid interviews, and a healthy dose of irreverence. From deep dives into ingredient science to raw conversations with dermatologists, brand founders, and industry insiders, each episode is a no-BS exploration of what really matters in skincare: how to attain and maintain healthy skin. If you’re obsessed with products, passionate about transparency, and love calling out hype, this is the place to learn, question, and glow smarter.The Skincarma® Blog is written and curated by skinfluencer, skincare junkie and Brooklyn writer Carmine Montalto. With 25 years of expertise in beauty across every category, Carmine has helped build multiple consumer brands from the ground up. He’s named 100s of skincare, haircare & makeup products – some of which are probably in your bathroom cabinet right now! And, he’s tested 1,000s of products, the best of which can be found reviewed on his blog at skincarma.com.With the right skincare routine including sunscreen...You CAN change your skin’s destiny!™ Get full access to Skincarma® at skincarma.substack.com/subscribe