”The Skinny-Fat Crisis” — Dr. Amy Shah on South Asian Genetics & The Cortisol Reset episode artwork

EPISODE · Feb 19, 2026 · 34 MIN

”The Skinny-Fat Crisis” — Dr. Amy Shah on South Asian Genetics & The Cortisol Reset

from Biohack-it · host Iman Hasan

I have been trying to get Dr. Amy Shah on Biohack-it for 18 months, and we finally made it happen while filming in Riyadh, Saudi Arabia. As two South Asian women, we dive straight into a conversation that hits close to home: why our race is built so petite yet remains at a significantly higher risk for type 2 diabetes, Alzheimer’s, and heart disease than other populations.In this episode, Dr. Amy Shah breaks down the fascinating science of "thrifty genes"—the biological survival mechanism from ancestral famines that makes our bodies hold onto sugar differently. We discuss the "skinny-fat" phenomenon and how modern lifestyle choices, like processed seed oils and a lack of protein, are creating a metabolic crisis. Dr. Shah shares her proprietary 30-3-3 rule for gut health and her signature "cortisol reset" to help you regulate your nervous system and reclaim your energy.Sponsors: Vibrant Wellness: Get the Hormone Zumra test to understand your body’s unique needs. Visit http://vibrant-wellness.com/imanhasan

I have been trying to get Dr. Amy Shah on Biohack-it for 18 months, and we finally made it happen while filming in Riyadh, Saudi Arabia. As two South Asian women, we dive straight into a conversation that hits close to home: why our race is built so petite yet remains at a significantly higher risk for type 2 diabetes, Alzheimer’s, and heart disease than other populations.In this episode, Dr. Amy Shah breaks down the fascinating science of "thrifty genes"—the biological survival mechanism from ancestral famines that makes our bodies hold onto sugar differently. We discuss the "skinny-fat" phenomenon and how modern lifestyle choices, like processed seed oils and a lack of protein, are creating a metabolic crisis. Dr. Shah shares her proprietary 30-3-3 rule for gut health and her signature "cortisol reset" to help you regulate your nervous system and reclaim your energy.Sponsors: Vibrant Wellness: Get the Hormone Zumra test to understand your body’s unique needs. Visit http://vibrant-wellness.com/imanhasan

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”The Skinny-Fat Crisis” — Dr. Amy Shah on South Asian Genetics & The Cortisol Reset

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This episode was published on February 19, 2026.

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I have been trying to get Dr. Amy Shah on Biohack-it for 18 months, and we finally made it happen while filming in Riyadh, Saudi Arabia. As two South Asian women, we dive straight into a conversation that hits close to home: why our race is built so...

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