Thiazide Diuretics and Hyponatremia

Hyponatremia is a side effect of most diuretics but the incidence from thiazides is unknown. Join host, Geoff Wall, as he evaluates a new study from Denmark evaluating hyponatremia and thiazides. The GameChangerThiazide diuretics are considered first-line therapy but electrolyte side effects are underevaluated. A new study suggests hyponatremia is significantly more common than previously reported, especially in the elderly. HostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint Health ReferenceAndersson NW, Wohlfahrt J, Feenstra B, et al. Cumulative Incidence of Thiazide-Induced Hyponatremia: A Population-Based Cohort Study. Ann Intern Med. 2023 Dec 19. doi: 10.7326/M23-1989. Epub ahead of print. PMID: 38109740.https://www.acpjournals.org/doi/abs/10.7326/M23-1989?journalCode=aim Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the use of thiazides in hypertension and their adverse effects 2. Assess the strengths and weaknesses of the Andersson et al study0.05 CEU/0.5 HrUAN: 0107-0000-24-032-H01-PInitial release date: 1/15/2024Expiration date: 1/15/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram