This Week in Critical Care — May 21, 2026

Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning advanced bedside diagnostics, mechanical ventilation, novel therapies for lung disease, and systems-level innovations in resuscitation and artificial intellige… This week's papers: 1. Point-of-care ultrasound in hemodynamically unstable pulmonary embolism. — Critical care (London, England) 2026 2. The FaciLItated hospital-based ECPR via Helicopter Transport (FLIGHT-to-ECPR) study. — Resuscitation 2026 3. Artificial Intelligence Algorithm to Monitor Inspiratory Muscle Effort and Patient-Ventilator Dyssynchrony During Mechanical Ventilation. — Critical care medicine 2026 4. Accuracy of electrical impedance tomography to detect perfusion defects in pulmonary embolism. — Critical care (London, England) 2026 5. Mitochondrial L-2-hydroxyglutarate is a physiological signalling metabolite. — Nature 2026 6. Sotatercept reduces bone morphogenetic protein signaling in patients with pulmonary arterial hypertension. — Science translational medicine 2026 7. The Association Between Mechanical Power and Mortality in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Systematic Review and Meta-Analy… — Critical care medicine 2026 8. Dupilumab in COPD: A Pooled Analysis of Emergency Department Visits, Hospital Admissions, and Systemic Corticosteroid Use. — American journal of respiratory and critical care medicine 2026 9. Multi-source data integration through pooling and transfer learning improves generalizability and specialization of deep learning models for ICU mortality and… — Critical care (London, England) 2026 10. Safety and efficacy of astegolimab for COPD with frequent exacerbations regardless of baseline blood eosinophil counts (ALIENTO and ARNASA): randomised, double… — Lancet (London, England) 2026 Listen at https://audioscholar.cc/episode/mfgz83u2ad