Three New Obesity Medicines With Dr. Marilyn Galindo episode artwork

EPISODE · Apr 6, 2026 · 29 MIN

Three New Obesity Medicines With Dr. Marilyn Galindo

from Modern Metabolic Health with Dr. Lindsay Ogle, MD · host Lindsay Ogle, MD

Today’s guest is a fellow board certified obesity medicine physician, Dr. Marilyn Galindo, founder of Leon Springs Obesity Medicine in San Antonio, Texas. Her practice is dedicated to provide compassionate and patient-centered care to individuals navigating the challenges of obesity. Dr. Galindo is also deeply committed to advocating for patients with obesity and helping them overcome the stigma and discrimination they often face. Follow Dr. Galindo on TikTok @marilyngalindomdWeight loss medicine is moving so quickly that it can be hard to tell what’s real progress and what’s just hype. Today we sit down with board-certified obesity medicine physician Dr. Marilyn Galindo to sort through the most talked-about “next” options and what they could mean for real people trying to improve metabolic health, reduce insulin resistance, and treat obesity as the chronic disease it is.We dig into high-dose semaglutide (Wegovy), including why higher dosing may unlock more total weight loss for some patients, what the studies show about variability in response, and which side effects may become more common as doses rise. We also talk about the practical art of prescribing GLP-1 receptor agonists: slowing down titration when needed, preventing constipation and dehydration, and why specialist-led care can improve long-term tolerability and adherence.From there, we explore cagriSema, a combination therapy that pairs semaglutide with an amylin analog to potentially boost satiety and support meaningful weight loss. One of the most interesting questions is whether amylin-based therapy could help with weight loss maintenance by blunting the metabolic slowdown that often follows weight reduction. If maintenance is the real finish line, this is the part to watch.We also cover orforglipron, a daily oral GLP-1 that may bring flexibility for people who dislike injections, travel often, or need simpler planning around surgery. Finally, we address what’s still in the pipeline, why buying unapproved drugs on the gray market is risky, and how we can keep pushing back on obesity stigma with evidence-based education.Subscribe, share this with someone who’s trying to make sense of modern obesity treatment, and leave a review so more people can find trustworthy metabolic health guidance.👩🏼‍⚕️ Live in Missouri? Want to be my patient?Telehealth clinic: https://missourimetabolichealth.com🥑 Have questions you want answered on the podcast? Email [email protected]✨Freebies✨Anti-Obesity Medication OptionsHow To Prevent DiabetesHealthy Habits WorkbookPreventative Health Checklist🤗 Socials:Instagram: https://www.instagram.com/dr.lindsayogle/TikTok: https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1YouTube: https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg

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Today’s guest is a fellow board certified obesity medicine physician, Dr. Marilyn Galindo, founder of Leon Springs Obesity Medicine in San Antonio, Texas. Her practice is dedicated to provide compassionate and patient-centered care to individuals navigating the challenges of obesity. Dr. Galindo is also deeply committed to advocating for patients with obesity and helping them overcome the stigma and discrimination they often face. Follow Dr. Galindo on TikTok @marilyngalindomd Weight lo...

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Three New Obesity Medicines With Dr. Marilyn Galindo

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This episode was published on April 6, 2026.

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