Treating Neuropsychiatric Symptoms in Parkinson's Disease

This paper serves as a comprehensive review of approaches for treating neuropsychiatric symptoms in Parkinson's disease (PD). It highlights that these non-motor symptoms are highly prevalent, significantly impair quality of life for both patients and caregivers, and often appear before motor symptoms. Despite recent advancements in diagnosis and management, treatment options, including both pharmacological and non-pharmacological therapies, remain limited due to the complex underlying brain changes in PD. The review summarizes current treatments for cognitive impairment, psychosis, depression, anxiety, apathy, and impulse control disorders, while also outlining ongoing research efforts to address the existing therapeutic gaps. Ultimately, the paper emphasizes that the treating neurologist's expertise is crucial for tailoring individualized treatment plans in this challenging context.