Tumor - Glioma Surgery: Antiseizure Medication Use in Seizure-Naive Patients

This episode reviews the clinical question surrounding routine antiseizure medication use in seizure-naive glioma patients undergoing surgery, drawing insights from a synopsis of the SPRING Randomized Controlled Trial. Published in Health Technology Assessment in 2026, this abstract-based discussion examines the prevalence of seizures in glioma patients and the current recommendations, which generally do not support routine prophylactic use. We explore the frequent perioperative prescription of levetiracetam despite these guidelines and discuss the potential clinical implications for patient management. This summary is for informational purposes and does not constitute medical advice. Always consult with a qualified healthcare professional for any medical concerns.