TWiN 30: Gut to brain spread of alpha-synuclein in Parkinson's disease

TWiN describes experiments demonstrating that gut injection of alpha-synuclein fibrils in mice converts endogenous alpha-synuclein to a pathologic form that spreads to the brain and leads to features of Parkinson's disease. Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Gut-brain alpha-synuclein transport in PD (Neuron) Gut has a mind of its own (Colbert Report) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to [email protected]