Understanding Lipedema at the Cellular Level

Today, I’d like to share research conducted at Tulane University in Louisiana, USA, titled "Increase in Leptin and PPAR-γ Gene Expression in Lipedema Adipocytes Differentiated in vitro from Adipose-Derived Stem Cells," published in the journal Cells in February 2020.The researchers aimed "to characterize the adipose-derived stem cells of healthy and lipedema patients." They found a significant difference between lipedema stem cells and those from healthy controls. Specifically, lipedema stem cells are more prone to produce fat cells that proliferate and exhibit increased inflammation.