Unexpectedly Low Rate of Metastasis & Death Among Patients Treated for Uveal Melanoma with Brachytherapy, Vitrectomy and Silicone Oil

The data from a cohort of my patients who live in Nevada took me by surprise. I acknowledge the work of Alex Rivas, a University of Nevada medical student and Dr. Wolfram Samlowski, a medical oncologist with uveal melanoma expertise who reached out to me and took action to publish our experience after noticing that our patients were not getting metastasis and dying like the existing data suggests should be the case.  The 5-year survival estimate in this cohort was 100%. Although small tumor size, disomy 3 and Class 1 accurately predicted a good prognosis, we found that the usual "high-risk" markers were not accurate. This meant that large tumor size, Monosomy and Class 2 patients that we treated continued to do well despite the odds. What was unique about this cohort? All were residents of Nevada. All were closely followed by Dr. Samlowski, and all had been treated by me. We don't know yet the mechanism of how vitrectomy and silicone oil may alter metastasis, but listen on to hear this story and reflections of changes necessary in this field. Link to full article here: https://www.mdpi.com/2072-6694/17/16/2683 For Tara McCannel's resources (including webinar links and link to my book!), visit my website: https://seyhart.com/ocularmelanoma Welcome to Finding Your Way with Ocular Melanoma, a guide to understanding everything there is to know about your experience with this rare cancer. Learn through the lens of my knowledge and clinical experience as a physician expert and passionate patient advocate. The more you know about ocular melanoma, the better you will do, and the better you will live. Let's go! The content shared on the Finding Your Way with Ocular Melanoma podcast is for informational and educational purposes only and does not constitute medical advice. The information provided must not be used as a substitute for professional medical advice, diagnosis, or treatment. As a listener, you are responsible for your own health-related decisions and must consider consulting with a healthcare professional for personalized medical advice.  Tara McCannel MD PhD is a an ocular oncologist, vitreoretinal surgeon and co-founder of Seyhart Wellness. She is also the host of the Mind Body MD podcast where she shares her passion for holistic health and wellness.