Unraveling the Histamine Puzzle with Functional Medicine

This week on ReInvent Healthcare, I tackle Histamines. I explore its underlying causes, symptoms, and how functional medicine offers a holistic approach to address this complex issue. Join me as I navigate the intricate pathways of histamine metabolism and discover evidence-based strategies to restore balance and promote overall well-being. Listen to the full episode to learn more. IN THIS EPISODE:Histamine IntoleranceThis refers to a condition where individuals experience adverse reactions to histamines in the body. Histamine intolerance can manifest as symptoms such as migraines, nasal congestion, hives, insomnia, and difficulty tolerating fermented foods. Histamine intolerance occurs when the body is unable to break down histamine efficiently due to a deficiency in enzymes like diamine oxidase (DAO) and histamine methyltransferase (HMNT).Causes and Factors of Histamine IntoleranceThere are several possibilities for the underlying causes of histamine intolerance.  Genetic variants can affect the body’s capacity for breaking down histamine. Imbalances in gut microbes, leaky gut syndrome, and mast cell activation can contribute to increased histamine production. Chronic exposure to allergens or harmful chemicals can also lead to higher histamine levels in the body.How To Manage HistaminesTaking antihistamines may not be the best solution. Several strategies can help manage histamine intolerance. These strategies include addressing nutrient imbalances, such as ensuring sufficient intake of vitamin B6, vitamin C and quercetin, which support histamine regulation. Certain supplements like DAO can aid in breaking down histamine. It may also be helpful to follow a low-histamine diet, avoiding high-histamine foods like aged cheeses, fermented foods, and leftovers. Additionally, supporting gut health, managing stress, and adopting a healthy lifestyle can contribute to reducing histamine intolerance symptoms.References:Get our FREE Guide to Taking a Detailed Health History that gets you to root causes with Access Additional Resources for Practitioners ready to improve clinical outcomes through our Nutritional Endocrinology Practitioner Training.  Purchase Dr. Ben Lynch’s Dirty Genes Histamine workbook here.