EPISODE · Jul 5, 2025 · 1H 5M
Upside #47 - Will AI Kill The Internet? IPO's Up? Can Doctors Beat AI?
from Upside · host Dan Bowyer & Mads Jensen - SuperSeed
🎙️ Upside #EP— IPOs, AI vs Doctors, London’s Trouble & The Internet’s Future⏱️ 02:30 – Figma’s IPO & European StakesFiling in NYC after failed Adobe acquisition$800M+ revenue, 91% margins, 132% NDR$5B Index Ventures paydayWhy this matters for Euro tech⏱️ 08:50 – London’s IPO DisasterWorst first half in nearly 30 years: only $160M raisedAstraZeneca flirting with a US listingCan London come back?25+ years of decline traced to pension reform post-Maxwell scandal⏱️ 14:10 – UK vs US Markets: Staggering ComparisonUS market cap: $60T vs UK: $3TTech in FTSE 100: only 1%Apple alone = FTSE 100Institutional apathy + structural rot⏱️ 18:00 – Pension Power & Mansion House DebateUK pension funds hold just 5% in UK equities£40B in annual tax breaks not translating into local investmentNeed for regulatory overhaul to unlock capital⏱️ 22:00 – Fixing the Public MarketsPublic markets *should* be the exit pathWithout them, the entire private capital waterfall stallsStagnation in public exits affects tax receipts, job creation, and the UK ecosystem⏱️ 25:45 – European Equities SurgeBiggest outperformance vs US stocks on record€46B inflows in 2025 vs €66B outflows in 2024Germany wakes up: €500B in infrastructure & defence spendSustainable or a short-term Trump-driven rotation?⏱️ 32:00 – UK Budget Black Hole£5B budget gap after Labour’s U-turnHighest tax burden since WWIISocial care + NHS = nearly 50% of budgetStuck between tax pledges, borrowing risks, and spending pressures⏱️ 41:00 – UK Future - 3-PathsStasis: stealth taxes, zero reformsFurther decline: shrinking influenceRecovery: bold reforms in pensions, NHS tech, and civil service productivityWhat road will we take?⏱️ 46:30 – EU AI Act: Incoming Train Wreck?Set for August rollout, but 44 major firms ask for pauseMissed code-of-practice deadline - What do we do?Healthcare, finance, and SaaS startups at riskGDPR 2.0 on steroids?⏱️ 52:45 – Can We Save the Open Web?Cloudflare’s bold move to gate AI scrapingAPI-first monetisation and licensing models emerging⏱️ 57:45 – AI vs DoctorsMicrosoft benchmark: AI got 80% of diagnoses right vs doctors’ 20%The end for doctors?Regulation, infrastructure, and explainability still big hurdles⏱️ 01:05:00 – Deal of the Week: Portal Biotech$35M Series A led by Earlybird + NATO Innovation FundProtein sequencing tech spun out of University of GroningenHopes to be “the Illumina of proteins”A deeptech win for Europe
What this episode covers
🎙️ Upside #EP— IPOs, AI vs Doctors, London’s Trouble & The Internet’s Future ⏱️ 02:30 – Figma’s IPO & European Stakes Filing in NYC after failed Adobe acquisition$800M+ revenue, 91% margins, 132% NDR$5B Index Ventures paydayWhy this matters for Euro tech⏱️ 08:50 – London’s IPO Disaster Worst first half in nearly 30 years: only $160M raisedAstraZeneca flirting with a US listingCan London come back?25+ years of decline traced to pension reform post-Maxwell scandal⏱️ 14:10 – UK vs US Mar...
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Upside #47 - Will AI Kill The Internet? IPO's Up? Can Doctors Beat AI?
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