Use of Bacteriophages as Natural Antimicrobials to Manage Bacterial Pathogens in Aquaculture in Vietnam and Australia

Aquaculture is the fastest-growing protein production industry globally, with Vietnam one of the top producers and exporters of seafood products. In Vietnam, aquaculture is seen as a means of protecting rural livelihoods threatened by the consequences of climate change on agriculture. But climate change also drives the emergence of marine bacterial pathogens, causing considerable losses to aquaculture production. Traditionally, pathogen blooms have been treated with antimicrobials – but this has resulted in the emergence and spread of antimicrobial resistance in aquaculture settings. So how can we combat these bacterial pathogens without fostering antimicrobial resistance whilst also continuing to produce the seafood needed to meet the world’s protein needs? Dr Carola Venturini is an expert research microbiologist and lecturer at the Sydney School of Veterinary Sciences at the University of Sydney. Her work investigates solutions to the crisis posed by the global rise in antimicrobial resistance in bacteria causing severe infections, with a particular focus on One Health/One World approaches. Her primary research areas are anti-microbial resistance transmission routes and mechanisms, impact of antibiotic use on gut health, and the design of bacteriophage-based applications against multidrug resistant pathogens, including in aquaculture settings in Australia and Vietnam. Dr Natali Pearson is Curriculum Coordinator at the Sydney Southeast Asia Centre, a university-wide multidisciplinary center at the University of Sydney, Australia. Her research focuses on the protection, management and interpretation of underwater cultural heritage in Southeast Asia.