Uterine aging plays a critical hidden role in IVF outcomes episode artwork

EPISODE · Feb 22, 2026 · 14 MIN

Uterine aging plays a critical hidden role in IVF outcomes

from The Podcast by KevinMD

Fertility specialist Oluyemisi Famuyiwa discusses her article "Uterine aging in IVF: Why the 'soil' matters as much as the seed." Oluyemisi explains that while clinicians often focus on egg quality, the aging of the uterus itself is a frequently overlooked factor in implantation failure. She explores clinical data showing that even with chromosomally perfect embryos, success rates decline as the endometrium loses its resilience due to cellular senescence and weakened progesterone signaling. The conversation challenges the standard "seed and soil" analogy by revealing that normal ultrasound thickness does not guarantee a receptive environment for pregnancy. Oluyemisi advocates for a precision medicine approach that scrutinizes the uterine environment as rigorously as the embryo to refine hope for patients. Discover how acknowledging the biological history of the uterus can transform unexplained failure into actionable data. Partner with me on the KevinMD platform. With over three million monthly readers and half a million social media followers, I give you direct access to the doctors and patients who matter most. Whether you need a sponsored article, email campaign, video interview, or a spot right here on the podcast, I offer the trusted space your brand deserves to be heard. Let's work together to tell your story. PARTNER WITH KEVINMD → https://kevinmd.com/influencer SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended

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Uterine aging plays a critical hidden role in IVF outcomes

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This episode was published on February 22, 2026.

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Fertility specialist Oluyemisi Famuyiwa discusses her article "Uterine aging in IVF: Why the 'soil' matters as much as the seed." Oluyemisi explains that while clinicians often focus on egg quality, the aging of the uterus itself is a frequently...

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