Vinod Khosla on softening the blow from AGI, and other future bets

In this episode recorded live at TechCrunch Disrupt 2025, TechCrunch's editor-in-chief, Connie Loizos, talks with Vinod Khosla about entrepreneurship in the age of AI and the massive disruptions ahead. They discuss why Khosla believes every profession represents a startup opportunity, his investment thesis of building AI workers rather than tools, and why he asks entrepreneurs to envision their company in 2030 before anything else. Khosla also shares his prediction that Fortune 500 extinction rates will triple by 2035, his controversial idea for sharing corporate wealth through a national pool, and why he thinks we'll have a hugely deflationary economy with free healthcare, education, and legal services. They also cover his early bet on OpenAI, the collision course between AI and climate (which he disputes), his investments in fusion and super-hot geothermal energy, and why the Trump administration's immigration policies represent "the worst damage possible" for American innovation. Learn more about your ad choices. Visit megaphone.fm/adchoices