Vision and the Brain (S2E23)

Summary: Humans experience and observe some of the most extravagant wonders and marvelous sights the world has to offer using the sense many of us sometimes take for granted ; Vision! How do eyes work? What role does the brain play in all of it ? Can we trust what we see ? Find out in this week’s episode of the neuroscience podcast. Quite literally, there is more than meets the eye! References: Bokkon, I. (2009). Visual perception and imagery: A new molecular hypothesis. Biosystems, 96(2), 178-184. doi: https://doi.org/10.1016/j.biosystems.2009.01.005 Collerton D., Dudley R., Mosimann U.P. (2012) Visual Hallucinations. In: Blom J., Sommer I. (eds) Hallucinations. Springer, New York, NY. Retrieved from https://link-springer com.subzero.lib.uoguelph.ca/chapter/10.1007/978-1-4614-0959-5_6#citeas Dubuc, B. (n.d.). The Brain from Top to Bottom: The Retina. Retrieved from http://thebrain.mcgill.ca/flash/i/i_02/i_02_cl/i_02_cl_vis/i_02_cl_vis.html Eagleman, D. M. (2001). Visual illusions and neurobiology. Nature Reviews Neuroscience, 2(12), 920-926. doi:10.1038/35104092 http://tinyurl.com/yarpmdfh Grossberg, S. (2014). How visual illusions illuminate complementary brain processes: Illusory depth from brightness and apparent motion of illusory contours. Frontiers in Human Neuroscience, 8, 854 http://tinyurl.com/y82ct4aw Kloosterman, N. A., Meindertsma, T., van Loon, A. M., Lamme, V. A. F., Bonneh, Y. S., & Donner, T. H. (2015). Pupil size tracks perceptual content and surprise in a visual illusion. European Journal of Neuroscience, 41, 1068-1078. http://tinyurl.com/y7xbzubk Ko, H., Cossell, L., Baragli, C., Antolik, J., Clopath, C., Hofer, S. B., & Mrsic-Flogel, T. D. (2013). The emergence of functional microcircuits in visual cortex. Nature, 496(7443), 96-100. doi:10.1038/nature12015 http://tinyurl.com/yb4dmw78 Manford, M., & Andermann, F. (1998). Complex visual hallucinations. Clinical and neurobiological insights. BRAIN, 121(10), 1819-1840. doi:https://doi.org/10.1093/brain/121.10.1819 Moffit, M., Brown, G., Salt, R., Simmons, M., & Ghebrehiwot, S. (Directors). (2017, May 4). Your Brain on LSD and Acid [Video file]. Retrieved from https://www.youtube.com/watch?v=wG5JyorwYPo Pfeffer, C. K., Xue, M., He, M., Huang, Z. J., & Scanziani, M. (2013). Inhibition of inhibition in visual cortex: The logic of connections between molecularly distinct interneurons. Nature Neuroscience, 16(8), 1068-1076. doi:10.1038/nn.3446 Roseman, L., Sereno, M. I., Leech, R., Kaelen, M., Orban, C., McGonigle, J., . . . Carhart-Harris, R. L. (2016). LSD alters eyes‐closed functional connectivity within the early visual cortex in a retinotopic fashion. Human Brain Mapping, 37(8), 3031-3040. doi:https://doi.org/10.1002/hbm.23224 Saleem, A. B., Ayaz, A., Jeffery, K. J., Harris, K. D., & Carandini, M. (2013). Integration of visual motion and locomotion in mouse visual cortex. Nature Neuroscience, 16(12), 1864-1869. doi:10.1038/nn.3567 http://tinyurl.com/ycl2wa6e Schmidt, F., Weber, A., & Haberkamp, A. (2016). Dissociating early and late visual processing via the ebbinghaus illusion. Visual Neuroscience, 33, E016. doi:10.1017/S0952523816000134 http://tinyurl.com/ycrsxyzb Serences, J. T., Ester, E. F., Vogel, E. K., & Awh, E. (2009). Stimulus-specific delay activity in human primary visual cortex. Psychological Science, 20(2), 207-214. doi:10.1111/j.1467-9280.2009.02276.x http://tinyurl.com/y7fw92vy Vollenweider F. X. (2001). Brain mechanisms of hallucinogens and entactogens. Dialogues in clinical neuroscience, 3(4), 265-79. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181663/ Other Resources: National Eye Institute (NIH) (Director). (2016, February 3). The Visual System: How Your Eyes Work [Video file]. Retrieved from https://www.youtube.com/watch?v=i3_n3Ibfn1c Hasudungan, A. (Director). (2016, May 24). Visual Pathway and Lesions [Video file]. Retrieved from https://www.youtube.com/watch?v=cG5ZuK0_qtc NIH: National Eye Institute. (2015, December). Facts About Retinitis Pigmentosa. Retrieve from https://nei.nih.gov/health/pigmentosa/pigmentosa_facts Alliance for Aging Research (Director). (2016, September 9). Taking a Closer Look at Age Related Macular Degeneration (AMD) [Video file]. Retrieved from https://www.youtube.com/watch?v=PUnLaG-XlDE