EPISODE · Apr 19, 2025 · 2 MIN
Voltage to Zero
from Base by Base - Music · host Gustavo Barcelos Barra
This release contains only the music track from Base by Base Episode 11. Song title: Voltage to ZeroOriginal Base by Base episode: 11: Mitochondrial Weakness: Targeting Dnmt3a-Mutant Clonal Hematopoiesis Article metadata:Article title: Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesisJournal: Nature CommunicationsDOI: 10.1038/s41467-025-57238-2Reference: Nature Communications (2025) 16:3306. DOI: 10.1038/s41467-025-57238-2 Lyrics:Verse 1In the marrow where the years sit heavy,Some cells learn how to outlast the crowd,They hum too bright, they pull power steady,Like a hidden wire turned up too loud. Pre-ChorusA single switch in the letters we carry,Loosens the locks on the nighttime code,So the engines rise, and the charge runs wary—A high-tension road. ChorusTurn that voltage to zero, let the bright line fade,If you live by the spark, you can’t dodge the blade,We aim for the pull that you can’t replace,Drop the membrane sky, watch the clone lose its place.Turn that voltage to zero—clean and clear,A future in the dark that we don’t have to fear. Verse 2Screens glow green with a steep oxygen climb,Spare capacity like a secret reserve,But the same high charge buys borrowed time,And a targeted key can make it swerve. BridgeLong-chain messenger, riding the gradient in,Finding the rooms where the charge is high,Shuts down the breath, lets the leak begin,Opens the gate—mitochondria sigh. Final ChorusTurn that voltage to zero, let the bright line fade,If you live by the spark, you can’t dodge the blade,We aim for the pull that you can’t replace,Drop the membrane sky, watch the clone lose its place.Turn that voltage to zero—hold the line,From crowded marrow to a cleaner time.
What this episode covers
This release contains only the music track from Base by Base Episode 11. Song title: Voltage to ZeroOriginal Base by Base episode: 11: Mitochondrial Weakness: Targeting Dnmt3a-Mutant Clonal Hematopoiesis Article metadata:Article title: Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesisJournal: Nature CommunicationsDOI: 10.1038/s41467-025-57238-2Reference: Nature Communications (2025) 16:3306. DOI: 10.1038/s41467-025-57238-2 Lyrics:Verse 1In the marrow where the years sit heavy,Some cells learn how to outlast the crowd,They hum too bright, they pull power steady,Like a hidden wire turned up too loud. Pre-ChorusA single switch in the letters we carry,Loosens the locks on the nighttime code,So the engines rise, and the charge runs wary—A high-tension road. ChorusTurn that voltage to zero, let the bright line fade,If you live by the spark, you can’t dodge the blade,We aim for the pull that you can’t replace,Drop the membrane sky, watch the clone lose its place.Turn that voltage to zero—clean and clear,A future in the dark that we don’t have to fear. Verse 2Screens glow green with a steep oxygen climb,Spare capacity like a secret reserve,But the same high charge buys borrowed time,And a targeted key can make it swerve. BridgeLong-chain messenger, riding the gradient in,Finding the rooms where the charge is high,Shuts down the breath, lets the leak begin,Opens the gate—mitochondria sigh. Final ChorusTurn that voltage to zero, let the bright line fade,If you live by the spark, you can’t dodge the blade,We aim for the pull that you can’t replace,Drop the membrane sky, watch the clone lose its place.Turn that voltage to zero—hold the line,From crowded marrow to a cleaner time.
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Voltage to Zero
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