Warfarin (Vitamin K Antagonist; VKA): Pharmacology Made Easy episode artwork

EPISODE · Jan 14, 2026 · 37 MIN

Warfarin (Vitamin K Antagonist; VKA): Pharmacology Made Easy

from This Is Why with Dr. Busti · host Anthony Busti, MD, PharmD, MSc, FNLA, FAHA

Warfarin (Vitamin K Antagonist; VKA) doesn’t have to be confusing. In this lecture from This is Why, Dr. Busti will explain warfarin's (Coumadin) pharmacology in a simple, clinically relevant way. It is perfect for anyone reviewing anticoagulation.You’ll learn how to:- Mechanism of action: how warfarin works as a vitamin K antagonist (VKA) (VKOR inhibition)- What PT/INR measures and why INR monitoring matters- How to start warfarin dosing (and what affects dose response)- Bridging with heparin/LMWH (warfarin bridge / heparin bridge) and when it’s needed- High-yield warfarin interactions (CYP2C9 inhibitors/inducers) + vitamin K foods- Warfarin reversal basics (including vitamin K reversal)The goal = make medical education easy and clinically relevant.👉 Access bonus materials and downloads from this episode at: https://www.thisiswhy.health/topics/warfarin-vka-coumadin-anticoagulants-pharmacology-review👉 Get more with a free membership at https://www.thisiswhy.health/- Access free downloads from our videos - Access deep dive content from Dr. Busti- Organize content via playlists & collections- Join live Q&A- Receive member newsletters- Coupons & discounts for exam prep resources👍 If this helped you, please like, subscribe, and share it with a classmate or colleague. That will help this new channel continue producing free, high-yield medical education content.🔔 Don’t forget to turn on notifications so you don’t miss upcoming lectures in pharmacology, medical rounds, and more!#WarfarinPharmacology #VitaminKAntagonist #WarfarinDosing #WarfarinInteractions #drbustiDisclaimer:This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.

Episode metadata supplied by the publisher feed · Published Jan 14, 2026

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Warfarin (Vitamin K Antagonist; VKA) doesn’t have to be confusing. In this lecture from This is Why, Dr. Busti will explain warfarin's (Coumadin) pharmacology in a simple, clinically relevant way. It is perfect for anyone reviewing anticoagulation. You’ll learn how to: - Mechanism of action: how warfarin works as a vitamin K antagonist (VKA) (VKOR inhibition) - What PT/INR measures and why INR monitoring matters - How to start warfarin dosing (and what affects dose response) - Bridging with ...

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Warfarin (Vitamin K Antagonist; VKA): Pharmacology Made Easy

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