What Causes Soft Plaque in Arteries and How To Reverse It episode artwork

EPISODE · Jul 14, 2026 · 6 MIN

What Causes Soft Plaque in Arteries and How To Reverse It

from The Healthspan Podcast · host HealthspanMD

Can you really reverse heart artery disease? In this episode, Dr. Robert Todd Hurst, MD, FACC, FASE, shares the remarkable story of a HealthspanMD member who thought he was doing everything right. Despite taking a statin, maintaining healthy blood pressure, staying active, and keeping his blood sugar under control, advanced imaging revealed he was still accumulating dangerous soft plaque in his coronary arteries. Dr. Hurst explains how plaque composition analysis works, why traditional cholesterol targets may not be enough for some people, and what happened when they implemented a more personalized strategy focused on achieving exceptional cardiovascular results. Today's guest is a HealthspanMD member with a strong family history of heart disease who was committed to protecting his heart health. After advanced CT angiography revealed significant soft plaque progression despite years of following conventional recommendations, he partnered with Dr. Robert Todd Hurst, MD, FACC, FASE, and the HealthspanMD team to take a more proactive, personalized approach. One year later, his results demonstrated what may be possible when root causes are identified and risk factors are optimized. Key Timestamps 00:03 – The patient's frustration despite doing everything "right." 00:45 – Understanding CT angiography and plaque composition analysis 01:32 – The concerning findings revealed by advanced imaging 02:15 – Why LDL goals below traditional guidelines may matter 03:00 – The strategy used to aggressively lower ApoB and LDL cholesterol 03:25 – One year later: the repeat CT angiogram results 03:45 – Soft plaque volume cut by more than half 04:00 – Low attenuation plaque reduced to zero 04:25 – What Dr. Hurst is seeing in patients with repeat plaque analysis testing 05:00 – Why guideline cholesterol targets may not be enough for everyone 05:35 – The seven root causes of coronary artery disease 06:05 – Lowering the risk of heart attacks, strokes, and dementia 06:45 – Can soft plaque disappear completely over time? 07:15 – Why proactive, personalized healthcare produces better outcomes 08:00 – The HealthspanMD philosophy for preventing and reversing heart disease Topics Discussed Reversing coronary artery disease Soft plaque vs calcified plaque CT angiography with plaque composition analysis ApoB and LDL cholesterol targets Coronary artery disease prevention Personalized cardiovascular medicine Root causes of heart disease Plaque regression Heart attack prevention Healthspan-focused healthcare   This information is for educational purposes only and is not medical advice. Don't make any decisions about your medical treatment without first talking to your doctor.   *Connect* *with* *HealthspanMD* : 👉 https://www.linkedin.com/company/healthspanmd/ 👉 https://www.facebook.com/healthspanmd 👉 https://www.instagram.com/healthspanmd/ 👉 https://open.spotify.com/show/5KQuoWqKP2vTBu05ci6EQB?si=fdb033a52b674909 👉 https://podcasts.apple.com/us/podcast/the-healthspan-podcast/id1680270608   🏆 Become a Member / 🤝 Partner With Dr. Hurst and His Expert Team To Add a Decade or More Of Healthy Life  At HealthspanMD, we combine cutting-edge medicine, advanced technology, and concierge care to help high-achievers avoid heart attacks, strokes, and dementia.    🔍 Learn how patients add years to their lives by going to 👉 https://www.healthspanmd.com.  📅 Or schedule a Call Directly with a HealthspanMD Dedicated Patient Advisor by clicking 👉 https://join.healthspanmd.com/call

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What Causes Soft Plaque in Arteries and How To Reverse It

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