What Happens to Your Brain When You Don_t Sleep _ Sleep Science

After seventeen hours without sleep, your reaction time matches someone with a blood alcohol level of 0.05 percent. After twenty-four hours, it matches 0.10 percent. After forty-eight hours, your brain begins to eat itself. This is not a metaphor.In this episode, I uncover the devastating effects of sleep deprivation on the brain. The glymphatic system, which clears toxic waste from the brain, only activates during deep sleep. Without it, amyloid beta and tau proteins accumulate, the same proteins linked to Alzheimer's disease. The prefrontal cortex, responsible for decision-making and impulse control, shuts down first. The amygdala, responsible for emotional reactions, becomes hyperactive. You become impulsive, irrational, and volatile.Microsleeps begin after thirty-six hours. Your brain forces two to three second blackouts without your permission. You can be standing, walking, even talking, and your brain is offline. Hallucinations begin after forty-eight hours. Shadow figures in your peripheral vision. Voices that are not there. After seventy-two hours, psychosis can set in. Delusions. Paranoia. Disorganized thinking. The brain is not designed to stay awake. It is designed to sleep.Turn down the lights, put on your headphones, and press play because staying awake is not a badge of honor. It is a form of self-destruction.