What if AI agents are the real reason blockchain was always going to matter? Yat Siu of Animoca Brands breaks it all down episode artwork

EPISODE · Apr 26, 2026 · 53 MIN

What if AI agents are the real reason blockchain was always going to matter? Yat Siu of Animoca Brands breaks it all down

from The Index Podcast · host Index Studios

Animoca Brands co-founder Yat Siu sits down with host Alex Kehaya to talk about digital ownership, the agentic economy, and why everything we built in Web3 was secretly a proof of concept for what's coming next. This one hits differently.Alex shares how Nansen went all-in on agentic AI, deploying 75 OpenClaws across their entire team, building shared skill repositories, and pioneering what he calls "claw fooding" — getting AI agents to test and fix their own product. We also get deep into agentic trading, Nansen's new CLI that lets your AI agent trade on-chain, and why Alex believes the traditional trading interface is dead.🔑 Key Topics Covered:🌐 Digital property rights & the case for true ownership — why most people are living in "rented space" online and what blockchain actually fixes🤖 The agentic economy is here — from 3–5 agents per person to potentially hundreds of billions roaming the open web💸 Agents need wallets — how crypto rails (payments, identity, wallets) are the perfect infrastructure for AI agents to transact freely🧠 Animoca Minds deep dive — how it deploys persistent agents in under 60 seconds, with shared infrastructure, long-term memory, and a skills marketplace⛓️ Why Solana's builder culture mattered — and how purpose-driven communities created ecosystems that survived the hardest moments🏗️ Orchestration vs LLMs — why the real value isn't which model you pick, but how you harness and own your agents🔓 Open source super intelligence as a human right — the stakes of letting a handful of companies own AGI, and how crypto + open source can counter that🌏 The cultural gap between AI and crypto — why Asia gets it and what the West needs to catch up on📌 Connect & Follow:🎙️ The Index Podcast:https://www.youtube.com/@theindexpodcast 👤 Yat Siu on LinkedIn: https://www.linkedin.com/in/yatsiu 🐦 Yat Siu on X: https://x.com/ysiu 🏢 Animoca Brands: https://www.animocabrands.com 🐦 Animoca Brands on X: https://x.com/animocabrandsShow LinksThe Index X ChannelYouTube

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Animoca Brands co-founder Yat Siu sits down with host Alex Kehaya to talk about digital ownership, the agentic economy, and why everything we built in Web3 was secretly a proof of concept for what's coming next. This one hits differently. Alex shares how Nansen went all-in on agentic AI, deploying 75 OpenClaws across their entire team, building shared skill repositories, and pioneering what he calls "claw fooding" — getting AI agents to test and fix their own product. We also get deep into ag...

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What if AI agents are the real reason blockchain was always going to matter? Yat Siu of Animoca Brands breaks it all down

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