What Niacinamide Studies May Reveal About Cancer as a Metabolic Disease

Glioblastoma is considered one of the most aggressive brain cancers, with survival often limited to about a year, largely because tumors adapt by rewiring how they use nutrients and energy Tumors divert vitamin B3 (niacinamide) away from normal energy production into a pathway that supports their survival, suggesting a metabolic weakness that could potentially be targeted This altered pathway may drain key cellular resources, meaning cancer cells appear to burn through materials they need to grow, which may create an opportunity to disrupt their fuel supply In a Science Advances study, high-dose vitamin B3 therapy was associated with improved short-term outcomes in patients, with over 80% showing no disease progression at six months in early findings, along with stronger immune activity against tumors Supporting your body's energy production and immune response through diet, lifestyle, and structured nutrient intake may help influence the same metabolic systems cancer depends on