What Science-First GPs Really Underwrite with Marie Lepske

Episode : What Science-First GPs Really Underwrite with Marie Lepske ;LP communication, technical diligence, fund design, and the sectors the market mispricesTimestamps :00:00 – Intro + Marie’s background01:28 – Fund thesis + sourcing engine05:02 –  Technical diligence + deep-tech underwriting11:40 - Fund construction + IC discipline22:08 – LP communication + cross-border capital map31:20 - Mispriced sectors + LP diligence questions + closeAbout Marie :Marie Lepske is a General Partner at Constructor Capital. Over her career, Marie has led over $50M in early-stage investments into 20+ deep-tech startups founded by scientists from Oxford, Harvard, and MIT, including leading companies in quantum computing and advanced technologies. With a background in applied mathematics and physics, and experience ranging from startup co-founder to chief of staff of a global technology group, she brings a rare perspective at the intersection of science, venture capital, and company building. Marie specializes in turning academic research into globally scalable businesses.Links:Marie Lepske - https://cy.linkedin.com/in/marie-lepskeConstructor Capital - https://constructor.capital/Emerging Forward Substack: https://emergingforward.substack.comEmerging Forward Spotify: https://open.spotify.com/show/6d7XPiIx4mekiPrgT03w5vEmerging Forward Apple Podcasts: https://podcasts.apple.com/us/podcast/emerging-forward-podcast/id1893666713 This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit emergingforward.substack.com