What Still Works for Building Muscle (After 50 Years of Research) – with Professor William Kraemer episode artwork

EPISODE · Apr 20, 2026 · 1H 16M

What Still Works for Building Muscle (After 50 Years of Research) – with Professor William Kraemer

from Stronger with Time · host Dr Tony Boutagy

After more than five decades of resistance training research, Professor William Kraemer returns to Stronger With Time to deliver a masterclass in what drives muscle growth, what the training protocols actually need to look like, and what has remained constant across every decade of evidence.Professor Kraemer has published over 600 peer reviewed papers and 15 books on resistance training, held professorships at four major universities, and been ranked the number one sports scientist in his field. His career spans both deep laboratory science and applied coaching with elite athletes across dozens of sports.In this episode, you will learn:Why the size principle remains the governing factor for muscle hypertrophy, and why fibres that are not recruited cannot growHow the anabolic hormonal response to resistance training actually works, and why testosterone does not act until it hits a receptorWhy excessive cortisol from poorly designed training may inhibit the very anabolic processes it was meant to stimulateWhy the eight to ten rep range at shorter rest periods of two to three minutes creates the most significant physiological stressorWhy 4×10 at moderate loads is often a bigger recovery demand than 3×3–5 heavy, and what that means for your weekWhy normative exercises form the foundation of any complete programme, and why angle variation is a necessary strategy for complete motor unit coverageWhat the evidence suggests for women navigating the menopause transition, and why the distinction between muscle function and muscle mass may be less meaningful than it appearsKey insight: After 50 years and over 600 papers, Professor Kraemer keeps returning to the same ground: load the muscle, recruit the fibres, manage the recovery. Everything else is context.Resources & LinksDr. Tony Boutagy → https://tonyboutagy.comFollow on Instagram → https://www.instagram.com/tonyboutagy/Professor William J. Kraemer Google Scholar → https://scholar.google.com/citations?hl=en&user=-HjoaV8AAAAJ

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