What to do when depression & antidepressants kill your libido: real talk & my story episode artwork

EPISODE · Dec 15, 2025 · 24 MIN

What to do when depression & antidepressants kill your libido: real talk & my story

from Pleasure Uprising: Desire, Attachment, and the Sex You Actually Want · host Laura Jurgens, Ph.D.

Depression tanks your libido. Then you finally get help with antidepressants—and your sex drive tanks even more. If this is you, you're not broken. You're dealing with a real, common side effect that nobody wants to talk about.In this episode, I break down the double whammy of depression and SSRIs on your sex life: how depression shuts down motivation (including for sex), why antidepressants compound the problem by affecting serotonin and dopamine, and how orgasm difficulties create a feedback loop that kills desire even further.I also share my personal story—how I dealt with depression, the mental scripts generating self-hatred that my brain was trying to protect me from, and how I got off meds through coaching and massive self-compassion work. Literally re-writing the thoughts in my head changed everything.We cover: what you can actually do about it (medication options, body-based approaches, relationship support), why this isn't your fault, and how to stop choosing between mental health and a satisfying sex life.Quick note: I'm not a medical doctor—this is educational, not medical advice. Always talk to your doctor about medication decisions.Get my free guide: Get Out of Your Head: A Starter Guide to Releasing the Pressure, Shame, and "Shoulds" Around Intimacy at https://laurajurgens.com/guideMore links: Substack at https://laurajurgens.substack.com/Pleasure Path Diagnostic here: https://laurajurgens.com/diagnostic/About me, testimonials, blog, bookings: https://laurajurgens.com/Wheel of Erotic emotions, go to: https://laurajurgens.com/wheelCopyright notice: All content in this podcast is copyrighted and copying, scraping, data mining, or using the content to train AI is prohibited. 

Depression tanks your libido. Then you finally get help with antidepressants—and your sex drive tanks even more. If this is you, you're not broken. You're dealing with a real, common side effect that nobody wants to talk about. In this episode, I break down the double whammy of depression and SSRIs on your sex life: how depression shuts down motivation (including for sex), why antidepressants compound the problem by affecting serotonin and dopamine, and how orgasm difficulties create a feedba...

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What to do when depression & antidepressants kill your libido: real talk & my story

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This episode was published on December 15, 2025.

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Depression tanks your libido. Then you finally get help with antidepressants—and your sex drive tanks even more. If this is you, you're not broken. You're dealing with a real, common side effect that nobody wants to talk about.In this episode, I...

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