What’s Going Wrong with The Infant Microbiome and Why Does it Matter? Episode 136

In this episode, Lisa talks with Stephanie Culler, PhD, co-founder and CEO of Persephone Biosciences and lead author of the My Baby Biome Study, the largest U.S. study profiling the infant gut microbiome.Stephanie explains why many modern babies are missing important species of bifidobacteria, even when they are born vaginally and breastfed. They discuss how birth practices, antibiotics, diet, breast milk, prebiotics, and environmental exposures may shape a baby’s developing microbiome.Lisa and Stephanie also explore the importance of avoiding parental guilt, why early microbial development may influence future health, and what families and healthcare professionals should look for when evaluating infant probiotic products.In this episode:Why bifidobacteria are considered foundational to the infant gutHow breast milk oligosaccharides feed beneficial bacteriaThe effects of cesarean birth and antibiotics on microbial developmentWhy breastfeeding remains important even when key bacteria are missingConnections being studied between the microbiome, eczema, allergies, and immune healthHow diet, fiber, fermented foods, and environmental exposure support microbial diversityWhat to consider when choosing a probiotic for an infantWhy clinical testing and strain-specific research matterHow restoring missing microbes may support the developing gut ecosystemLearn more about the work of Stephanie Culler, PhD here: Persephone.bio.More from Tongue Tie ExpertsExplore additional resources, including downloads, free guides, and links mentioned in this episode—along with access to our courses and new book:👉 www.tonguetieexperts.net/LinksUse code PODCAST15 for 15% off all offerings.This podcast is meant for education and conversation only. It is not medical advice and does not replace formal education, professional training, or individualized care from a qualified healthcare provider. Always seek appropriate guidance for individual concerns. The views and opinions shared by our guests are their own and do not necessarily reflect those of the host or Tongue-tie experts.